Halifax Health – Cancer Center for Hope is the only cancer center in East Central Florida to offer an innovative treatment for men with metastatic prostate cancer, Pluvicto®. This new therapy provides targeted treatment specifically for PSMA-positive metastatic hormone-resistant (also known as castrate-resistant) prostate cancer, and it is FDA-approved.
Metastatic prostate cancer poses significant treatment challenges. The number of men diagnosed with metastatic prostate cancer is on the rise, with data from the Centers for Disease Control and Prevention showing that diagnoses increased from 4% to 8% between 2003 and 2017.
Although Pluvicto is not a cure, it can extend life and improve quality of life while minimizing side effects.
Pluvicto is a precision-targeted radioligand therapy designed to treat metastatic prostate cancer by delivering radiation directly to PSMA-positive cancer cells. It targets cancer cells that have spread to other parts of the body and is administered via injection or infusion. The treatment consists of six infusions, approximately six weeks apart.
Patients eligible for Pluvicto must have metastatic prostate cancer that is hormone-resistant and tumors that express high levels of PSMA, as confirmed by a PSMA PET/CT scan. Additionally, candidates should have cancer that has progressed after undergoing standard chemotherapy.
Eligibility criteria include:
Prostate cancer not responding to hormone treatments aimed at lowering testosterone levels
Evidence of cancer that has spread to other parts of the body
Positive PSMA expression on imaging
Pluvicto functions as a radiopharmaceutical combining a targeted drug with a radioactive particle. The drug component binds to the PSMA protein on prostate cancer cells, enabling the delivery of radiation directly to these cells. The process effectively damages and kills PSMA-positive cancer cells while sparing healthy surrounding tissue. Pluvicto’s mechanism shares similarities with Lutathera®, another radiopharmaceutical approved by the FDA for cancer treatment.
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Benefits and Risks of Pluvicto
As with any treatment, side effects may occur.
Common side effects include:
› Dizziness, fatigue, or weakness
› Dry mouth
› Changes in weight
› Constipation or stomach pain
› Headaches and altered taste
› Diarrhea, nausea, and reduced appetite
› Low blood counts
› Potential kidney dysfunction
Halifax Health - Cancer Center for Hope is at the forefront of cancer diagnosis and treatment in East Central Florida. Here’s what you can expect from our comprehensive services:
Whether you’re seeking chemotherapy, hematology, immunotherapy, or radiation therapy, Halifax Health is committed to attacking cancer from every angle while providing compassionate care for patients and their families.
Remember that you’re not alone in this journey, and our team is here to support you every step of the way.
The center is committed to innovative treatments and clinical trials that offer patients cutting-edge options like Pluvicto, enhancing both survival and quality of life. For more information and to find out if Pluvicto is right for you, contact Halifax Health – Cancer Center for Hope at 386.425.HOPE, or visit Pluvicto.
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